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Cystitis in Cats: Symptoms, Treatment & Prevention

Est. read time: 7 min.

If you've ever noticed your cat straining in the litter box, vocalizing in discomfort, or suddenly avoiding the litter box altogether, you might be dealing with cystitis. As a veterinarian and cat mom, I know firsthand how distressing it can be to see your feline friend in pain. Understanding what cystitis is, how it differs from other urinary issues, and what you can do to prevent it can make all the difference in your cat’s health and well-being.

What is cystitis in cats?

Cystitis is inflammation of the bladder. Unlike a urinary tract infection (UTI), which is caused by bacteria, feline cystitis can be sterile (meaning no infection is present). It’s a common condition in cats and often part of a broader disease complex called feline lower urinary tract disease (FLUTD). Cystitis can be acute (short-term) or chronic (recurring), and while it can resolve on its own, it can also lead to more serious complications needing ongoing treatment.

Cystitis vs. UTI vs. FLUTD: What’s the difference?

While these conditions can have overlapping symptoms, they are distinct:

  • Cystitis: Inflammation of the bladder, often idiopathic (unknown cause) or stress-related.
  • Urinary tract infection (UTI): A bacterial infection affecting the bladder or urinary tract, more common in older cats or those with other health issues.
  • Feline lower urinary tract disease (FLUTD): An umbrella term for various conditions affecting a cat’s bladder and urethra. FLUTD is most commonly observed in middle-aged, overweight cats experiencing stress—such as changes in routine, moving to a new environment, or living in a multi-cat household.

Persian cat pee on bed

Symptoms of cystitis in cats

Cats with cystitis may display one or more of the following symptoms:

If you notice any of these signs, it’s essential to take action quickly. Cystitis can be painful and, in some cases, may indicate a more serious underlying issue.

Types of cystitis in cats

There are several types of cystitis, including:

  • Idiopathic (sterile) cystitis: The most common form, often linked to stress and environmental factors rather than infection.
  • Bacterial cystitis: Less common but can occur, especially in senior cats or those with diabetes or kidney disease.
  • Urolithiasis (bladder stones): Crystals and stones can irritate the bladder and cause inflammation.

Diagnosing cystitis in cats

A veterinarian will use a combination of diagnostic tests to determine the cause of cystitis and rule out other urinary issues. These may include:

  • Urinalysis: Evaluates urine for blood, crystals, abnormal pH levels, and signs of infection or inflammation.
  • Urine culture: Identifies bacteria and what antibiotic it’s susceptible to in cases where an infection is suspected.
  • X-rays: Detects bladder stones or anatomical abnormalities.
  • Ultrasound: Provides a detailed view of the bladder wall, identifying thickening, polyps, or other abnormalities.
  • History and physical exam: Helps assess potential triggers such as stress, diet, or environmental changes.
  • Additional testing: In complex cases, contrast imaging or biopsies may be needed for a definitive diagnosis.

Treatment for cystitis in cats

Since most cases of feline cystitis are not caused by infection, antibiotics are rarely needed. Treatment generally focuses on:

  • Pain management: anti-inflammatory medications, muscle relaxants
  • Increasing water intake: wet food, water fountains, or broth
  • Stress reduction: consistent routines, calming pheromones, and environmental enrichment
  • Prescription urinary diets: to reduce bladder irritation and encourage a healthy bladder environment
  • Antibiotics: when an infection is present

Is cystitis in cats an emergency?

While cystitis itself isn’t always an emergency, it can quickly become one if a male cat develops a urethral obstruction. 

A blocked cat is unable to urinate, which can cause life-threatening kidney failure within 24-48 hours. If your male cat is straining but not producing urine, seek emergency veterinary care immediately. Otherwise, if you start to notice some of the symptoms above, schedule an appointment with your veterinarian for a checkup.

Is cystitis a lifelong condition?

The duration of cystitis in cats depends on the underlying cause. Some cases of acute cystitis may resolve on their own or with treatment, while chronic feline idiopathic cystitis (FIC) can be a recurring issue throughout a cat’s life. Cats prone to stress-induced cystitis may experience flare-ups periodically, making long-term management essential. With the right approach—hydration, diet modifications, stress reduction, and routine veterinary care—many cats can live comfortably, even if they have recurrent episodes.

Preventing cystitis in your cat

Prevention is key to avoiding painful recurrences. Here’s how to keep your cat’s urinary system healthy:

  • Encourage hydration: Use water fountains, add water to food, or offer broths.
  • Feed a balanced diet: Veterinary urinary health diets can help prevent crystal formation and irritation.
  • Minimize stress: Use calming supplements or pheromones. Products like Feliway can help reduce stress-related flare-ups.
  • Offer environmental enrichment: More play, hiding spots, and scratching posts can reduce stress.
  • Ensure a clean litter box: Some cats avoid dirty boxes, which can lead to holding urine too long. Scoop often or try a self-cleaning litter box
  • Regular vet check-ups: Catching early signs of urinary issues can prevent severe cases.

cat using Litter-Robot 4 while woman is on Whisker app

How Litter-Robot has helped cats with cystitis 

Litter-Robot automatic litter boxes provide a clean bed of litter every time your cat has to go thanks to advanced self-cleaning technology. This is especially useful for cats that avoid dirty litter boxes, particularly in multi-cat households.

Additionally, the Whisker app will notify you every time your cat uses the litter box. If you notice a major spike in activity, you can act fast by taking your cat to the vet or the emergency clinic. 

“My 7 y.o. female Domestic Shorthair struggled with idiopathic cystitis for YEARS. We tried enrichment, multiple medications, a water fountain, wet food, all the things, more litter boxes, different styles and types of boxes and litter… we even moved to a bigger place and it still continued. She would pee blood and also pee in random places all over our house. It was so incredibly frustrating. I honestly didn’t think the Litter-Robot would make a difference - I got it pretty much because I was tired of scooping and was also hoping it would help control odor. But literally, after purchasing our Litter-Robot over a year ago, she hasn’t had a single flare up. I can’t promise this will miraculously cure your cats’ health issues but it has been the only thing to work for mine.” Ana, Litter-Robot 4 user

“Why didn't I get this sooner? My cat with cystitis requires a very clean litter box or he won't use it. This solves the problem. It is worth every penny.” Donna, Litter-Robot 4 user

“Litter-Robot saved our cat’s life. I noticed one day that the app was going off every 10 minutes. I went [to the unit], saw a little bit of blood, and realized we better take him to the vet. They diagnosed him with feline idiopathic cystitis. I wouldn’t have known something was wrong without Litter-Robot.” Ariana, Litter-Robot 3 Connect user

Final thoughts

Cystitis in cats can be frustrating to deal with, but with proper care, most cases can be managed effectively. By recognizing symptoms early, reducing stress, and supporting hydration, you can help prevent painful flare-ups. If your cat is showing signs of urinary discomfort, don’t wait—talk to your vet to ensure the best treatment plan.

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